![]() ![]() These studies extend our definition of the processes that MTOCs regulate. However, cytological studies performed between 19 depict the involvement of MTOCs in membrane related events. Centrosomes, spindle pole bodies, and related structures, generally termed microtubule organising centres (MTOCs Pickett-Heaps 1969), are best understood in the context of their function in the organisation of the mitotic spindle, spindle positioning via astral microtubule organisation, and regulation of cell cycle checkpoints (Doxsey 2001 Pereira and Schiebel 2001). ![]()
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